We compared exercise performance among patients with mild to moderate essential hypertension treated by long-acting nifedipine, atenolol, and non-medication. All of the patients underwent a treadmill exercise test based on Bruce's protocol. Heart rate (HR) and blood pressure (BP) responses were recorded at rest, 1 minute after beginning exercise, at peak exercise, and at 1, 3, and 5 minutes after peak exercise. The pressure rate product (PRP) was calculated in each group. To clarify the age-related differences, we also compared those responses between the younger (<60 years) and the elderly group (>60 years). In conclusion, long-acting nifedipine dose not contribute to improved exercise performance, particularly in younger patients. The results of the exercise suggest that atenolol does have a favorable effect in younger patients with hypertension.
KAORU NAKAZATO, KAZUTOSHI MINAMITANI, YUJI NAKAZATO, HIROYUKI SATO, Exercise Performance in Patients with Essential Hypertension Treated with Atenolol or Long-Acting Nifedipine Journal of the Hong Kong College of Cardiology 1999;7(1):3-7 https://doi.org/10.55503/2790-6744.1478