Device therapy has become the preferred treatment for patients who have survived sudden cardiac death. Throughout the last decade, large-scale randomized clinical trials have provided consistent evidence on the clinical efficacy of device therapy. ICD is proven to be superior to anti-arrhythmic drugs in patients with structural heart diseases who suffer from haemodynamically significant ventricular arrhythmias. The role of ICD in primary prevention of sudden death in selected patients with coronary artery disease and left ventricular dysfunction is also widely established after the Multicenter Automatic Defibrillator Implant Trial (MADIT) and the Multicenter Unsustained Tachycardia Trial (MUSTT).
Kathy Lai-Fun Lee, Chu-Pak Lau, The Post-MADIT II Era: ICD for all Post-infarct Patients with Moderate to Severe Left Ventricular Dysfunction? Journal of the Hong Kong College of Cardiology 2002;10(3) https://doi.org/10.55503/2790-6744.1189
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